'2DG'- Drug for Covid-19 patients
What is '2-DG'
On monday, May 17 , DRDO (Defense Research Development Organization) released the first batch of the indigenously developed anti-Covid-19 drug, '2-DG' abbreviated as 2-deoxy-D-glucose. 2DG is an oral drug.
On May 1, The national drug regulator, Drug Controller General of India (DCGI) granted permission for the emergency use as an adjunct therapy in moderate to sever COVID-19 patients.
2-DG has been developed by INMAS (Institute of Nuclear Medicine and Allied Sciences) and DRDO (Defense Research Development Organization) in collaboration with Hyderabad based pharma company,Dr. Reddy's laboratories.
How it Works?
The drug accumulates in virus infected cells and prevents the growth of the virus by stopping viral synthesis and energy production.
2-DG molecules helps patients to recover faster and reduces their dependence on supplemental Oxygen.
It's selective accumulation in viral infected cells makes this drug unique.
(Pic credit- StudyIQ YouTube Channel)
In general, infected cells have more receptor than healthy cells so to cut down the glucose supply to these infected cell this replicated glucose is used which kills the infected cells and thus, further generation and mutation of new cell aborts.
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